Custom DNA Synthesis: antisense (phosphorothioated) oligos

Phosphorothioated oligonucleotides (PTO)

Synthesis scale	Additional charge per PTO base	Basic cost per base	Setup charge
0.2 umole	US$1.50* / CAN$2.00 per PTO base	US$0.48* / CAN$0.74	$0.00
1.0 umole	US$1.50 / CAN$2.23 per PTO base	US$1.50 / CAN$2.23	$0.00
15 umole	US$10.00 / CAN$15.00 per PTO base	US$6.50 / CAN$10.00	US$30 / CAN$50

* Example: One oligo of 20 bases at the 200 nmole scale, of which 3 bases at each end are phosphorothioated; 20 x 0.48 = 9.60, plus (3+3) x 1.50 = 9.00, for the total of 18.60.