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100 or 200 nmole scale* |
1000 nmole scale |
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(non-equimolar mix, also known as "doping") |
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| 3'-end 6-FAM, HEX or TET |
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US$29 / CAN$45 |
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5' TAMRA (may replace NED) |
US$80 / CAN$120 |
US$180 / CAN$270 |
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3' Cy3 dye |
US$80 / CAN$100 |
US$150 / CAN$200 |
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3' Cy5 dye |
US$80 / CAN$100 |
US$150 / CAN$200 |
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5' Cy5 dye (may replace D4) |
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5' Cy5.5 dye (may replace D3) |
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5' Texas Red (may replace PET, ROX or Cy3.5) |
(US$67 / CAN$100 for 4th and consecituve dye per order) |
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Yakima Yellow (may replace VIC) |
(US$100 / CAN$120 for 4th and consecituve dye per order) |
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2'-O-Me RNA |
US$4 / CAN$6 |
US$8 / CAN$12 |
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one oligo from the same type of modification |
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*200 nmole (0.2 micromole) scale synthesis will yield typically 0.1-0.2 micromole (100-200 nmole) final product. Guaranteed minimum 50 nmole for regular size (up to 25-mer) oligos, standard purity (desalted). For longer oligos, 10 OD260 guaranteed minimum (standard purity). Standard purity includes free desalting. All oligos are quantified and three different units of measure are provided to the customer. The exact relation between these three units is calculated by a computer for each oligo; as a very rough approximation for a 20 base long oligo, 100 nmole equals about 20 OD260 units, or 600 microgram. Example of price calculation for one oligonucleotide, 20-mer, 100 nmole scale, 5'-end labeled with 6-FAM: 20 x 0.29 = 5.80 basic price of the oligo, plus 29.00 for the 6-FAM, total = 34.80 USD.
Phosphorothioated oligonucleotides (PTO)
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Synthesis scale
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Additional charge per PTO base
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Basic cost per base
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Setup charge
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0.2 umole
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US$1.50** / CAN$2.00 per PTO base |
US$0.48** / CAN$0.74
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$0.00
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1.0 umole
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US$1.50 / CAN$2.23 per PTO base
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US$1.50 / CAN$2.23
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$0.00
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15 umole
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US$10.00 / CAN$15.00 per PTO base
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US$6.50 / CAN$10.00
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US$30 / CAN$50
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