|
Type of modification |
Price per insertion, |
Price per insertion, |
|
Degenerated bases |
$0.00 |
$0.00 |
|
Degenerated bases |
US$3 / CAN$5 |
US$6 / CAN$10 |
|
5' Acrydite |
US$40 / CAN$60 |
US$80 / CAN$120 |
|
Inosine (deoxyinosine, dI) |
US$6.67 / CAN$10 |
US$13 / CAN$20 |
|
Uridine (deoxyuridine, dU) |
US$6.67 / CAN$10 |
US$13 / CAN$20 |
|
3' Phosphorylation |
US$15 / CAN$23 |
US$30 / CAN$45 |
|
5' Phosphorylation |
US$24 / CAN$35 |
US$48 / CAN$70 |
|
3' Amine |
US$15 /CAN$23 |
US$30 / CAN$45 |
|
5' Amine - C6 |
US$24 / CAN$35 |
US$48 / CAN$75 |
|
3' Thiol |
US$25 / CAN$37 |
US$50 / CAN$75 |
|
5' Thiol |
US$40 / CAN$60 |
US$80 / CAN$120 |
|
3' Biotin |
US$25 / CAN$37 |
US$50 / CAN$75 |
|
5' Biotin |
US$39 / CAN$60 |
US$78 / CAN$120 |
|
3' Cholesterol |
US$70 / CAN$100 |
US$140 / CAN$200 |
|
5' Cholesterol 1 insertion/order 2 insertions/order 3 or more insertions/order |
US$200 / CAN$260 US$110 / CAN$150 US$80 / CAN$110 |
US$400 / CAN$520 US$220 / CAN$300 US$160 / CAN$220 |
|
3' Digoxigenin |
US$120 / CAN$180 |
US$240 / CAN$360 |
|
5' Digoxigenin |
US$120 / CAN$180 |
US$240 / CAN$360 |
|
3'-end 6-FAM, HEX or
TET |
US$49 / CAN$74 |
US$149 / CAN$223 |
|
5'-end 6-FAM, HEX or
TET |
US$29 / CAN$45 |
US$75 / CAN$120 |
|
3' BHQ-1(black hole
quencher) |
US$50 / CAN$75 |
US$100 / CAN$150 |
|
3' BHQ-2 |
US$50 / CAN$75 |
US$100 / CAN$150 |
|
3' BHQ-3 |
US$50 / CAN$75 |
US$100 / CAN$150 |
|
3' Dabcyl |
US$49 / CAN$74 |
US$99 / CAN$149 |
|
5' TAMRA (may replace NED) |
US$80 / CAN$120 |
US$180 / CAN$270 |
|
3' TAMRA |
US$49 / CAN$74 |
US$149 / CAN$223 |
|
5' Fluorescein (FITC) |
US$24 / CAN$36 |
US$50 / CAN$75 |
|
3' Fluorescein Labeling |
US$25 / CAN$37 |
US$50 / CAN$75 |
|
3' Cy3 dye |
US$80 / CAN$100 |
US$150 / CAN$200 |
|
5' Cy3 dye |
US$80 / CAN$100 |
US$150 / CAN$200 |
|
3' Cy5 dye |
US$80 / CAN$100 |
US$150 / CAN$200 |
|
5' Cy5 dye (may replace D4) |
US$80 / CAN$100 |
US$150 / CAN$200 |
|
5' Cy5.5 dye (may replace D3 and LC-Red 705) |
US$160 / CAN$200 |
US$300 / CAN$400 |
|
3' Redmond Red (may replace TxRed, PET, ROX or Cy3.5) |
US$70 / CAN$100 |
US$140 / CAN$200 |
|
5' Texas Red (may replace PET, ROX or Cy3.5) |
US$120 / CAN$150 |
US$200 / CAN$250 |
|
3' Yakima Yellow (may replace VIC) |
US$70 / CAN$100 |
US$140 / CAN$200 |
|
5' Yakima Yellow (may replace VIC) |
US$200 / CAN$250 |
US$400 / CAN$500 |
|
2'-O-Me RNA |
US$4 / CAN$6 |
US$8 / CAN$12 |
|
Other modifications |
Please inquire |
Please inquire |
|
Discounts for more
than
|
Please inquire |
Please inquire |
*200 nmole (0.2 micromole) scale
synthesis will yield typically 0.1-0.2 micromole (100-200 nmole) final
product. Guaranteed minimum 50 nmole (shorter oligos) or 10 OD units (longer oligos), desalted, non-modified oligos. Standard purity
includes free desalting. Modified oligos may have considerably lower
yields. All oligos are quantified and three different units of measure
are provided to the customer. The exact relation between these three
units is calculated by a computer for each oligo; as a very rough approximation
for a 20 base long oligo, 100 nmole equals about 20 OD260 units, or 600
microgram. Example of price calculation for one oligonucleotide, 20-mer,
100 nmole scale, 5'-end labeled with 6-FAM: 20 x 0.29 = 5.80 basic price
of the oligo, plus 29.00 for the 6-FAM, total = 34.80 USD.
Phosphorothioated oligonucleotides (PTO)
|
Synthesis
scale |
Additional
charge per PTO base |
Basic
cost per base |
Setup
charge |
|
0.2
umole |
US$1.50**
/ CAN$2.00 per PTO base |
US$0.48**
/ CAN$0.74 |
$0.00 |
|
1.0
umole |
US$1.50
/ CAN$2.23 per PTO base |
US$1.50
/ CAN$2.23 |
$0.00 |
|
15
umole |
US$10.00
/ CAN$15.00 per PTO base |
US$6.50
/ CAN$10.00 |
US$30
/ CAN$50 |
**Example:
One oligo of 20 bases at the 200 nmole scale, of which 3 bases at each end are
phosphorothioated: 20 x 0.48 = 9.60, plus (3+3) x 1.50 = 9.00, for the
total of 18.60.
©
1997-2010 Alpha DNA
